Search Northeast Missouri hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Northeast Missouri
Family friendly
Check prices for these dates
Our top choices for Northeast Missouri hotels
9.2 out of 10, Wonderful, (1505)
"Good transport to and from car rental, a plus
"
Ralph
The price is AU$189
includes taxes & fees
29 Dec - 30 Dec
9.2 out of 10, Wonderful, (1002)
"this is the perfect place to stay the night before going to the airport "
Laurie
The price is AU$206
includes taxes & fees
4 Jan - 5 Jan 2026
9.4 out of 10, Exceptional, (2761)
"Great place to stay before your early morning flight. "
Henry
The price is AU$158
includes taxes & fees
1 Jan - 2 Jan 2026
8.8 out of 10, Excellent, (3039)
"Clean room, good breakfast and good location "
Martin
The price is AU$164
includes taxes & fees
28 Dec - 29 Dec
9.4 out of 10, Exceptional, (841)
"Clean, would stay again."
Eryka
The price is AU$185
includes taxes & fees
29 Dec - 30 Dec
Fairfield Inn & Suites by Marriott St. Louis Downtown
Fairfield Inn & Suites by Marriott St. Louis DowntownDowntown West
9.2 out of 10, Wonderful, (1000)
"Breakfast menu was fresh and tasty. Will return in the future with more time to go to the national park!"
Silvar
The price is AU$190
includes taxes & fees
25 Jan - 26 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Northeast Missouri, MO
Showing deals for:9 Jan - 11 Jan
Image gallery for Up Up and Away Lodging
Up Up and Away Lodging
Hermann
9.4/10Exceptional (27 reviews)
10% off
Price is AU$1,055
for 2 nights, 1 room
AU$528 per night
includes taxes & fees
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Northeast Missouri
Great live music, sports teams and popular sights from St. Louis Union Station to Busch Stadium—explore Northeast Missouri, a family-friendly destination also known for its theatres.
Top Northeast Missouri Hotel Reviews
Recent Reviews in Northeast Missouri
The Wildwood Hotel
10/10 Excellent
More cheap accommodation in Northeast Missouri
Relax Inn Saint Charles
3800 Harry S Truman Blvd St. Charles MO
The price is AU$105 per night from 28 Dec to 29 Dec
AU$105
28 Dec - 29 Dec
includes taxes & fees
6.4/10 (1,002 reviews)
Explore a world of travel with Expedia
- Alexandria Hotels
- Cheap Hotels in Cairo
- Hotels with Pool in Cairo
- Luxury Hotels in Cairo
- Cairo Hotels
- B&B in Canton
- Hotels with Pool in Canton
- Luxury Hotels in Canton
- Canton Hotels
- Clark Hotels
- Downing Hotels
- Edina Hotels
- Ethel Hotels
- Excello Hotels
- Gibbs Hotels
- Cabin Rentals in Hannibal
- Lgbt Welcoming Hotels in Hannibal
- Hannibal Hotels
- Luxury Hotels in Huntsville
- Huntsville Hotels
- B&B in Kahoka
- Chalets in Kahoka
- Holiday Homes in Kahoka
- Kahoka Hotels
- Kirksville Hotels
- B&B in La Grange
- La Grange Hotels
- Luxury Hotels in La Plata
- La Plata Hotels
- Motels in La Plata
- Pet Friendly Hotels in Macon
- Winery Hotels in Macon
- Macon Hotels
- Madison Hotels
- Hotels near Mark Twain Casino
- Hotels near Mark Twain Memorial Lighthouse
- Family Hotels in Memphis
- Luxury Hotels in Memphis
- Memphis Hotels
- Motels in Memphis
- Business Hotels in Monroe City
- Monroe City Hotels
- New Cambria Hotels
- New London Hotels
- B&B in Palmyra
- Cheap Hotels in Palmyra
- Palmyra Hotels
- Motels in Palmyra
- Farmstay in Paris
- Cheap Hotels in Paris
- Luxury Hotels in Paris
- Paris Hotels
- Motels in Paris
- Golf Hotels in Perry
- Perry Hotels
- Rutledge Hotels
- Saverton Hotels
- B&B in Shelbina
- Shelbina Hotels
- Cheap Hotels in Shelbyville
- B&B in Taylor
- Holiday Homes in Taylor
- Taylor Hotels
- Flights to Clark County
- Flights to Scotland County
- Flights to Atlanta
- Flights to Baring
- Flights to Cairo
- Flights to Center
- Flights to Elmer
- Flights to Florida
- Flights to Hannibal
- Flights to Huntsville
- Flights to Jacksonville
- Flights to Kirksville
- Flights to Macon
- Flights to Madison
- Flights to Memphis
- Flights to Moberly
- Flights to Newark
- Flights to Paris
- Flights to Taylor
- Flights from Kirksville Municipal
- Flights from Melbourne (MEL) to Kirksville (IRK)
